Genetic Variants Associated with FDNY WTC-Related Sarcoidosis
نویسندگان
چکیده
منابع مشابه
NOD2 genetic variants and sarcoidosis-associated uveitis☆
Purpose Identifying genetic risk factors for developing sarcoidosis-associated uveitis could provide insights into its pathogenesis which is poorly understood.We determine if variants in NOD2 confer an increased risk of developing uveitis in adults with sarcoidosis. Methods In this genetic case-control study, 51 total subjects were enrolled: 39 patients diagnosed with sarcoid-related uveitis ...
متن کاملInteraction of Insulin Resistance and Related Genetic Variants With Triglyceride-Associated Genetic Variants.
BACKGROUND Several studies suggest that some triglyceride-associated single-nucleotide polymorphisms (SNPs) have pleiotropic and opposite effects on glycemic traits. This potentially implicates them in pathways such as de novo lipogenesis, which is presumably upregulated in the context of insulin resistance. We therefore tested whether the association of triglyceride-associated SNPs with trigly...
متن کاملWorld Trade Center "sarcoid-like" granulomatous pulmonary disease in New York City Fire Department rescue workers.
BACKGROUND Previous reports suggest that sarcoidosis occurs with abnormally high frequency in firefighters. We sought to determine whether exposure to World Trade Center (WTC) "dust" during the collapse and rescue/recovery effort increased the incidence of sarcoidosis or "sarcoid-like" granulomatous pulmonary disease (SLGPD). METHODS During the 5 years after the WTC disaster, enrollees in the...
متن کاملGenetic Variants Associated with Colorectal Adenoma Susceptibility
BACKGROUND Common low-penetrance genetic variants have been consistently associated with colorectal cancer risk. AIM To determine if these genetic variants are associated also with adenoma susceptibility and may improve selection of patients with increased risk for advanced adenomas and/or multiplicity (≥ 3 adenomas). METHODS We selected 1,326 patients with increased risk for advanced adeno...
متن کاملGenetic variants associated with sleep disorders
OBJECTIVE The diagnostic boundaries of sleep disorders are under considerable debate. The main sleep disorders are partly heritable; therefore, defining heritable pathophysiologic mechanisms could delineate diagnoses and suggest treatment. We collected clinical data and DNA from consenting patients scheduled to undergo clinical polysomnograms, to expand our understanding of the polymorphisms as...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Environmental Research and Public Health
سال: 2019
ISSN: 1660-4601
DOI: 10.3390/ijerph16101830